Hair Loss Medications
The right approach depends on the type and stage of hair loss, your medical history and your individual treatment goals. At Parissis Medical, we offer personalised guidance on a range of evidence-based hair loss medications and can help determine whether medication, hair transplant surgery or a combination of treatments may be suitable for you.
What do we offer?
We offer in-depth consultations to assess your:
Current Level of Hair Loss
Family History of Hair Loss
Likely Hair Loss Progression
Best Medication Options
The Big Problem
The hair loss medication industry is filled with snake oils and potions that make it difficult to distinguish between what is helpful and what isn’t.
Below is a brief summary of the main hair loss medications that are evidence-based.
01
Oral Finasteride
5-alpha reductase blockers like Finasteride are first line for Male Pattern Baldness. They work by stopping the conversion of testosterone to DHT. DHT is the hormone responsible for hair loss and therefore by reducing DHT levels, we can slow down hair loss.
02
Topical Finasteride
Topical finasteride reduces scalp DHT with minimal systemic absorption. Studies show results comparable to oral finasteride in improving hair density. Side effects are less common, though long-term data is limited. A promising option for men seeking effective, lower-risk treatment.
03
Oral Dutasteride
Dutasteride has good research to suggest it is a powerful 5-alpha reductase blocker – reducing DHT levels by more than 90%. However, research also suggests this translates to ~50% reduction in scalp DHT – meaning it still only slows down hair loss and doesn’t stop it for good.
04
Topical Dutasteride
Topical Dutasteride has limited research to support it’s safety and effectiveness. It is therefore not routinely prescribed for patients. However, one can imagine it is effective but the more important question is – does it go into the bloodstream and therefore cause side effects? If so, this would defeat the purpose of it’s topical use – which is hailed as one of the best benefits of topical formulations.
05
Topical Minoxidil
Minoxidil is known as a ‘hair growth stimulator’. The exact mechanism of action is unknown but the main working theory is that it prolongs the ‘anagen’ or ‘growing’ phase of the hair – giving thicker, faster growing and longer hair in some patients.
06
Oral Minoxidil
Oral minoxidil is a more recent update to the more widely used topical form.
It enhances hair growth by increasing blood flow and extending the growth phase. Research shows strong results for both men and women, even when topical options fail. Side effects like fluid retention or increased body hair are usually mild and dose-dependent. A convenient, effective option for those seeking fuller, thicker hair.
07
Ketoconazole
Ketoconazole was once thought of as a useful medication for hair loss.
Overall, there are two conclusions from the research:
1) Randomized controlled trials need to be done to be more sure.
2) Studies so far suggest that ketoconazole is a SUPPLEMENTARY option for those who want to squeeze out more hair gains – NOT a big ‘needle-mover’. In other words it is unlikely to make a big difference to your hair growth.
08
Saw Palmetto
- The research is mixed
- A Systematic Review by Evron et al from 2020 has at least some efficacy against AGA
- It’s lack of side effects compared to finasteride do suggest it could be a possible alternative for select patients
- These patients could be those who get side effects from finasteride and/or want to avoid pharmaceuticals
- It is likely effective as an adjunct compound with minoxidil.

